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Health & Fitness

INTERNATIONAL SCIENTIFIC CONFERENCE ON ENTOMOLOGY AND PEST 2026

By fadilawati ali

ISCEP 2026 At Sunway Putra Hotel 17-18 August 2026

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Published
Aug 15, 2026
Pages
102
Language
English

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ABSTRACT

ORAL PRESENTATION ABSTRACT

T3.04

INVOLVEMENT OF DETOXIFICATION ENZYMES IN INSECTICIDE RESISTANCE AMONG AEDES ALBOPICTUS FROM AGRONOMICAL AREAS OF WEST MALAYSIA

Othman WAN-NORAFIKAH, Chee Dhang CHEN', Mohd SOFIAN-AZIRUN

Faculty of Medicine, UniveTakologi MARA (LT) Selangor Branch, Sungai Buloh Campur Sungai Bul Selangor, Malaya

"HW Real Live Teknologi MARA (UTM Shah Alam, Selangor Malaya

Travel Research Laboratory; Research Facilities Centre Department of Research Development, Uni Malaya, Kuala Lumpur, Malaya

Sa Presectability and Con tute of Biological Sciences, Faculty of Science, Univ horafiah@utmedumy

ABSTRACT

Malayalam

The extensive use of insecticides to control mosquito vectors can lead to the development of insecticide resistance, with increased metabolic enzyme activity serving as a primary mechanism. This study ascertained the involvement of detoxification enzymes in insecticide resistance among Aedes albopictus from agronomical areas in West Malaysia. Enzyme microassays for non-specific esterases (EST), mixed function oxidases (MFO), glutathione- S-transferases (GST), and insensitive acetylcholinesterase (AChE) were conducted on Ae. albopictus larvae and adults. Significantly elevated a-EST activity was exhibited in As. albopictus adults from all three types of agronomical areas, while significantly elevated a-EST activity was observed only in Ae. albopictus adults from rice cultivation areas and rubber estates. Elevations in larval a-EST and a-EST activities, alongside MFO activity in both larvae and adults across all area types, were statistically insignificant. Significantly elevated GST activity at the larval stage was discovered in Ae. albopictus populations from bath rice cultivation areas and rubber estates; however, at the adult stage, this elevation was only demonstrated in Ae. albopictus from rice cultivation areas. Furthermore, findings from the AChE enzyme microassay showed the effectiveness of proposar as an adulticide across all agronomical areas, though it was only effective in controlling Ae. albopictus larvae within oil palm plantations. In brief, the involvement of each detoxification enzyme in insecticide resistance pathways across different life stages of Ae. albopictus was autonomous and varied. Further studies are required to broaden our understanding of the roles of detoxification enzymes in the metabolic resistance of mosquitoes.

INTERNATIONAL SCIENTIFIC CONFERENCE ON ENTOMOLOGY AND PEST SCEP) 2006

Keywords: Aedes albopictus, insecticide resistance, detoxification enzymes, Malaysia