ISCEP 2026 At Sunway Putra Hotel 17-18 August 2026
ABSTRACT
ORAL PRESENTATION ABSTRACT
T3.03
RESISTANCE PROFILING OF AEDES AEGYPTI USING INTENSITY CONCENTRATIONS ENHANCES THE EVALUATION OF INSECTICIDE EFFECTIVENESS FOR VECTOR CONTROL
Basli ROSILAWATI, Misrawi NORLAILI, Rosli SHAZREENA', Ariffin FARAH DIANA', Kamarudin NUR AMALINA', Abdul Razak SHAIRAH', Wan KIEW-LIAN²
Medical Enterology Unit, Infectious Disease Research Centre of Health, Ministry of Heath, Shah Alam, Selangor, Malay Department of logical Sciences and Biotecheology. Facahy of Science and Technology Univers
Kabangan Malaysia, Bangi Selangor, Malaysia for Medical Research National
'Department of Applied Physics, Faculty of Science and Technology Utara Kebangsaan Malaya Selangor, Malaysia [email protected]
ABSTRACT
The detection of insecticide resistance is pivotal for characterising the phenotypic resistance of field- collected Aedes aegypti, facilitating early identification of resistance trends to safeguard the efficacy of chemical interventions in vector control programmes. While the World Health Organization (WHO) adult tube test is the standard screening method, its reliance on binary resistance and susceptibility data limit the ability to categorise insecticides by their degree of resistance across insecticides. To address this, a probit analysis of adult mortality of a field collected strain from discriminating and intensity bioassay, was performed. The LC values were normalised using the concentration ratio framework. The conelation between the concentration ratio data matrix and the slope of field strains across various insecticides was evaluated, enabling the inference of resistance magnitude. The results demonstrate that primiphco-methyl showed high efficacy, whereas significant intra-population variability in resistance intensity existed among pyrethroids and malathion, with lambda-cylin ohibited the highest resistance, followed by permethrin and alpha-cypermethrin Utilising mortality data derived from WHO-recommended discriminating and interaity concentrations enables a more detailed evaluation of resistance beyond the binary classification of standard susceptibility tests. Such data-driven strategies are essential to improve the interpretation of insecticide resistance profiling. They provide a clearer picture of current resistance status, ultimately allowing for more informed decision-making regarding insecticide rotation in vector control programmes.
Keywords: dengue, pynthroids, intensity resistance, WHO adult assay Aedes aegyp
INTERNATIONAL SCIENTIFIC CONFERENCE ON ENTOMOLOGY AND PEST SCP) 2005