Basic Information
Tests for PMOS / PCOS
Common Hormonal Disorder In Women of Reproductive Age
Polyendocrine Metabolic Ovarian Syndrome (PMOS), previously known as Polycystic Ovary Syndrome (PCOS), is a complex multi-system disorder. Core Characteristics: It is driven by multiple hormonal imbalances and insulin resistance, affecting ovulation, metabolism, and skin health. Symptoms : Reproductive: Irregular or missed menstrual cycles, anovulatory infertility, reduced sex drive. Androgenic: Hirsutism (excess body/facial hair), severe acne, male-pattern hair thinning. Metabolic Dysregulation: Weight gain, fatigue, dark skin patches (acanthosis nigricans), mood changes.
Rationale for Renaming PCOS to PMOS * PCOS was renamed Polyendocrine Metabolic Ovarian Syndrome (PMOS) because "cysts" is a misnomer (they are immature follicles, not true cysts). The old label wrongly framed a multisystem condition as purely ovarian. "PMOS" accurately reflects its underlying multi-hormonal and long-term metabolic impacts. Screening Tests
Basic Interpretation
Elevated LH with low or normal FSH LH: FSH ratio greater than 2:1 indicates ovulatory dysfunction
AMH (Anti-Müllerian Hormone) Elevated levels reflect an increased pool of small antral follicles.
Metabolic Screening Fasting Glucose Fasting Insulin, HOMA Score
Further Confirmation
Androgens Total & Free Testosterone, DHEA- S, Androstenedione
Elevated levels confirm clinical or biochemical hyperandrogenism and help rule out androgensecreting tumors.
Reduced levels account for increased circulating free, active testosterone.
Evaluated to systematically rule out hypothyroidism, hyperprolactinemia, non-classical congenital adrenal hyperplasia, or pregnancy.
Identifies polycystic ovarian morphology (multiple small immature follicles) and evaluates structural features.
*Ref:Teede, H., Piltonen, T., Dokras, A., Cree, M., et al. (2026). Polyendocrine Metabolic Ovarian Syndrome (PMOS): The Lancet, Published online May 12, 2026.